Saturday, August 29, 2009

Gordon Woods, Mule Cloning Researcher, Has Died


One of the most ironically but fitting aspects of the advent of equine cloning in the United States is that the pioneer clones were not graceful show horses or robust athletes but champion racing mules from the Northwest who received genes not just for racing but for personality of their species.

Pioneering scientists who wanted to be taken seriously were always a bit in danger of being upstaged by their product.

One of those pioneers died this week. Dr Gordon Woods led the team at the University of Idaho that produced the world’s first equine clone – a perfect mule foal named Idaho Gem – on May 4, 2003. Idaho Gem’s brothers – Utah Pioneer and Idaho Star – were born later that year. The accomplishment thrust the team’s research onto the international stage.

As scientifically and commercially significant as the cloning was to the horse industry, Dr. Woods was most excited about further exploring the connection between the cellular biology that led to the clone success and the cellular activity associated with age-onset diseases in humans such as cancer, diabetes and Alzheimer’s Disease. After the cloning project, he continued to use the horse as a model for better understanding human health, and moved on to Colorado State University, where he was working at the time of his death.

Dr Woods earned his doctor of veterinary medicine degree at Colorado State University in 1975 and completed his residency in large animal reproduction at the University of Pennsylvania, New Bolton Center. He then enrolled at the University of Wisconsin where he worked with Dr. O.J. Ginther and earned his master’s and doctoral degrees in reproductive biology. He joined the faculty of the New York State College of Veterinary Medicine at Cornell University in 1983 as an assistant professor.

He returned to Idaho in 1986, founding the Northwest Equine Reproduction Laboratory and teaching at Washington State University and later at the University of Idaho where he served as a professor in the Department of Animal and Veterinary Science. In 2007, he moved his program to Colorado State.

He founded a private company, CancEr2, to explore basic research on the physiological bases of cancer and also served as president of EquinE2, a company created to commercialize horse reproduction technology and was a principal in another company, ClonE2, which was formed to offer horse cloning services commercially.

Donations in Dr Woods' memory may be sent to a fund at "Colorado 4-H Foundation/OMK," Colorado State University Extension, 4040 Campus Delivery, Fort Collins CO 80523-4040.

Thanks to Colorado State University for their help with this news. I remember when all three of the cloned mules were going to run in the same race. I'm very sorry to hear that we've lost Dr. Woods, after having written so many articles about his work and the mules. He truly was a pioneer.

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Thursday, April 9, 2009

Clones Will Be Left at the Gate in Oklahoma if Governor Signs Legislation

by Fran Jurga | 9 April 2009 | The Jurga Report

Thanks to our friends at the Quarter Horse Racing Journal and American Quarter Horse Association for the "ears up" about horse-related legislation in Oklahoma that is headed for the Governor's office to be signed.

No, it's not equine dentists this time: The AQHA announced yesterday that Oklahoma has banned clones and (if I am reading this article correctly) their offspring from racing in the state.

Click here to read the Racing Journal's article.

An article in the Oklahoman newspaper has some quotes but some of the points aren't quite clear, since it is unlikely that clones themselves would be racing anyway.

It seems to me that the whole point of commercial cloning (vs sentimental cloning of a pet) is for breeding. Legislation like this would take a lot of wind out of cloning's sails. And sales. It's interesting that the clones would be banned from racing but not showing or commercial breeding or sales.

The story gets even murkier when you get down to realizing that if the AQHA doesn't even register clones, this is a "just in case" piece of legislation--in effect, closing the barn door before the clone gets out.

Will clones have a big C branded into their foreheads for all to see? They look just like other horses, after all, and their offspring will too. And a clone's DNA test will not look like something from a mountaintop in Transylvania.

The cloning story continues to write itself, right in front of our eyes. I urge you all to read more about this fascinating subject. Sooner or later, no matter where you live or no matter what breed of horse you may show or race or breed or own, or what equestrian sport discipline you choose, you'll be hearing about cloning.

This subject has rekindled my interest in equine reproduction, which had been eclipsed by my total obsession with lameness for many years. When the first clone goes lame, it will be my story.

Click here for a one-stop archive of recent articles here on the Jurga Report about the AQHA's struggle with finding a reasonable resolution to this issue.

And stay tuned, both to this blog and AQHA sources for more cloning news as it happens.

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Saturday, February 7, 2009

Send in the Clones: Forum on American Quarter Horse Clone Registration Rule Change Will Be Available via Webcast

One of the biggest changes in the history of American horse breeding has been set in motion, but you don't have to travel to San Antonio, Texas on March 6 to be part of it.

American Quarter Horse Association members who can’t make it to the equine cloning forum at the 2009 AQHA Annual Convention will be able to watch the event online in the members section of www.aqha.com. The forum Webcast will begin at 2 p.m. March 6.

You must be an AQHA member and have a Personal Identification Number to log in at the site and access the Webcast.

Under Rule 227(a) of the AQHA official handbook, a rule that became effective in 2004, American Quarter Horses produced by any cloning process are not eligible for registration. Clones are currently not being bred for performance use, but rather for breeding, so the offspring of a clone would not be able to registered.

All that may change in March.

The AQHA Stud Book and Registration Committee (SBRC) first considered a proposed change to Rule 227(a) at the 2008 AQHA Convention. That proposed change would allow a live foal produced via a particular type of cloning to be registered if its DNA matches that of a registered American Quarter Horse. Voting on that rule change was postponed to 2009 while more information was gathered.

The proposed change to Rule 227(a) will again be on the SBRC agenda at the 2009 AQHA Convention but only after a public forum where members will be able to learn more about cloning and to express their opinions. This forum is open to all interested AQHA members.

Confirmed forum panelists include Katrin Hinrichs, a veterinarian involved in equine cloning at Texas A&M University; Sharon Spier, an epidemiologist at the University of California-Davis; George Seidel, a professor specializing in biomedical sciences at Colorado State University; and Blake Russell of ViaGen, a commercial cloning lab.

Following the forum, AQHA members watching the webcast will have the opportunity to leave online comments on the information presented. Comments will be limited to 100 words and need to be related to the topics presented during the forum.

For more information on cloning, see the February issue of The American Quarter Horse Journal, the March issue of The American Quarter Horse Racing Journal and the March-April issue of America’s Horse.

Blogger's Note: My copy of the Journal came in the mail today and contained an eight-page article called "Pure Genetics", which covers many aspects of the cloning issue.

In 2008, the National Cutting Horse Association passed a rule allowing clones to compete. Champion cutting horse Smart Little Lena was cloned five times in 2006 by Texas A&M University, according to the AQHA article. Offspring sired by any of the five would currently not be eligible for registration with the AQHA, but would be able to compete in NCHA events. Might clones become part of a distinct new breed association?

After the AQHA convention in March, they might be welcome in the AQHA for the first time. Other breed associations would then need to decide whether to follow the AQHA's lead; currenty no breed associations register clones.

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